| 2022-07-23 18:00:41Jul 23, 2022 |   Chicago Portagers at Milwaukee Muskies | 12 - 7 | Great Plains Box Lacrosse League | 2022 | Ozaukee Ice Center |
| 2022-08-06 11:00:55Aug 6, 2022 |   Minneapolis Wheat Kings at Chicago Portagers | 9 - 8 | | 2022 | Salt Creek Sports Center |
| 2022-08-06 13:00:14Aug 6, 2022 |  Missouri Mastodons at Chicago Portagers | 15 - 13 | Great Plains Box Lacrosse League | 2022 | Salt Creek Sports Center |
| 2022-08-13 18:00:32Aug 13, 2022 | Chicago Portagers at Milwaukee Muskies | 11 - 12 | Great Plains Box Lacrosse League | 2022 | Ozaukee Ice Center |
| 2022-08-14 15:00:51Aug 14, 2022 |  Chicago Portagers at Madison Milkmen | 17 - 3 | Great Plains Box Lacrosse League | 2022 | Sauk Prairie Ice Arena |
| 2022-08-20 15:00:46Aug 20, 2022 | Madison Milkmen at Chicago Portagers | 3 - 18 | Great Plains Box Lacrosse League | 2022 | Salt Creek Sports Center |
| 2022-08-27 15:00:36Aug 27, 2022 | Milwaukee Muskies at Chicago Portagers | 8 - 11 | Great Plains Box Lacrosse League | 2022 | Salt Creek Sports Center |
| 2022-08-28 14:00:37Aug 28, 2022 | Chicago Portagers at Madison Milkmen | 12 - 8 | Great Plains Box Lacrosse League | 2022 | Sauk Prairie Ice Arena |
| 2022-09-10 15:00:31Sep 10, 2022 | Milwaukee Muskies at Chicago Portagers | 12 - 14 | Great Plains Box Lacrosse League | 2022 | Salt Creek Sports Center |
| 2022-09-17 15:00:16Sep 17, 2022 | Madison Milkmen at Chicago Portagers | 6 - 24 | Great Plains Box Lacrosse League | 2022 | Salt Creek Sports Center |
| 2022-09-18 14:00:25Sep 18, 2022 |  Chicago Portagers at Iowa Dogfish | 12 - 11 | Great Plains Box Lacrosse League | 2022 | The Rivers Edge |
